ethyl 3-(o-tolyl)pyrrolidine-3-carboxylate - Names and Identifiers
ethyl 3-(o-tolyl)pyrrolidine-3-carboxylate - Introduction
ethyl 3-(o-tolyl)pyrrolidine-3-carboxylate is an organic compound with the chemical formula C15H19NO2.
Nature:
ethyl 3-(o-tolyl)pyrrolidine-3-carboxylate is a colorless liquid. It has a strong aromatic smell. The compound has a density of 1.08 g/mL, a melting point of -25°C and a boiling point of 204-206°C. It is soluble in alcohol and ether solvents.
Use:
ethyl 3-(o-tolyl)pyrrolidine-3-carboxylate is commonly used as an intermediate in organic synthesis. It can be used in the synthesis of various drugs, pharmaceutical intermediates and pesticides and other organic compounds.
Method:
The synthesis of ethyl 3-(o-tolyl)pyrrolidine-3-carboxylate is usually completed by the following steps: First, o-toluidine is reacted with acetone to generate O-tolylvinylmethylamine; O-tolyl vinyl methylamine is then reacted with a glycolic acid decarboxylating agent to produce ethyl 3-(o-tolyl)pyrrolidine-3-carboxylate; Finally, 3-(o-tolyl) ethyl pyrrolidine-3-carboxylate reacts with a base to give ethyl 3-(o-tolyl)pyrrolidine-3-carboxylate.
Safety Information:
ethyl 3-(o-tolyl)pyrrolidine-3-carboxylate has low toxicity, but some safety precautions still need to be observed. It is a flammable liquid and should be kept away from fire and high temperatures. Wear appropriate protective gloves and eye protection when using. Avoid inhaling vapors or touching skin. In case of accidental contact, rinse immediately with plenty of water and seek medical help. Attention should be paid to fire and explosion prevention measures during storage and handling.
Last Update：2024-04-09 21:01:54